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Research offers clues for treating fatal neurological disorder in kids

School of Medicine news release •
In this slide, bright green staining shows the massive buildup of material that occurs inside brain cells when their lysosomes, the cells’ waste disposal and recycling system, are defective. This occurs in CLN1 disease, a fatal neurological disorder that affects infants and young children, because a vital lysosomal enzyme is missing. Research in animals led by Washington University in St. Louis and the Roslin Institute in Scotland shows that supplying this missing enzyme helps improve the condition.
In this slide, bright green staining shows the massive buildup of material that occurs inside brain cells when their lysosomes, the cells’ waste disposal and recycling system, are defective. This occurs in CLN1 disease, a fatal neurological disorder that affects infants and young children, because a vital lysosomal enzyme is missing. Research in animals led by Washington University in St. Louis and the Roslin Institute in Scotland shows that supplying this missing enzyme helps improve the condition.
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